ANTIHYPERURICEMIA ACTIVITY OF WUALAE FRUIT (Etlingera elatior Jack R. M. Smith) ETHANOL EXTRACT IN VIVO

Plants Etlingera elatior (Wualae) is a family Zingiberaceae of ​​the genus which has large population in the world. The E. plant widely used empirically community to increase endurance and seasoning fruit.
 In this study, ethanol extract was determine its potential effectiveness as an antihyperuricemia (in vivo) tested pharmacologically on Rattus novergicus L. twenty-four rats were grouped into six groups, namely wualae fruit at dose (100 mg/kgBW, 200 300 400 mg/kgBW), negative control group Sodium CMC 0 .5%, positive Allopurinol 10 mg/kgBW. Furthermore, To value uric acid levels, first induced with 250 mg/kgBW Potassium Oxonate via intraperitoneal (i.p). preparation according treatment given orally one hour later after administration potassium oxonate. At (1, 2, 3), blood taken intravenously (i.v) through rat's tail, then level analyzed photometer. All doses 100, 200, 300, showed that they could reduce overall. effective (300 mg/kgBW). This research can be concluded (Jack) R.M. Smith (uric acid) developed traditional medicine